This profile (https://www.digitalcombatsimulator.com/en/files/3300626/) is the one I'm trying to use. Loading the config in TARGET causes the stick to become unresponsive. Disabling the profile the stick is still unresponsive until I unplug it and plug it back in.
edit: to clarify, the joystick no longer responds in Windows. I have to unplug and plug it back in for the controller config to register movement/button presses from the joystick.