there's an option in the saitek software enable/disable clutch. I have it disabled so that it responds to the profile, it didn't when that option was enabled (it's my gear keypress).
rclick the x52 icon in tray, choose control panel. On the MFD page uncheck 'enable clutch mode'
Make sure that the trackir center key in the profile is the same as in trackir _And_ make sure the key is not also used in DCS :)
This is the profile Im using: X52 DCS A-10C.zip