Anyone having problems with certain keys like = [ ' / with their saitek x52,I think this will resolve your issues.I have windows xp media center and still use the old dat. files with my x52 and had this problem. start your profile in saitek then go to your device manager,then keyboard,I had 5 drivers installed,3 for e-home(media center).I uninstalled those,left with 2,hid driver and ps2 driver.when you check the drivers for the ps2,their are 2,one for the multimedia and one standard.Pick the standard to install,then close out. You can verify this by going to your profile and check if your keys work correctly now,mine do.
Hope this helps some,drove me nuts for awhile but it works great now.
p.s. when you shutdown your puter and restart,all the drivers are back installed so no harm done.