I usually play multiplayer PVE Servers, so recently I've found that my usual loadout below can help tackle most scenarios while keeping it somewhat realistic.
1. ALQ-184
2. GBU-12
3. 2x AGM-65D's
4. 7x MPP APKWS
5. GBU-54
6. usually nothing
7. GBU-54
8. 7x MPP APKWS
9. 2x AGM-65D's
10. targeting pod
11. 2x aim9m's
I'll load up with 80% fuel, full combat mix gun ammo and a countermeasure mix of 120 chaff/ 180 flares. I'll expand most of the stores on a sortie, except for a gbu-54 here and there. That is if I don't get shot down by SAMS halfway through. The flight performance in better than average with only 80% fuel. I've only messed around with the laser mavericks once and rifled two off on a jtac laser spot. Now that was cool.