I had the same issue from the start with the SU-25T. My setup is not great but all other weapons worked fine - only the Vikhrs create a noticeable FPS drop.
However, when I got to a specific campaign mission it got worse to the point of severe lag ending up in complete freeze of DCS.
I tried to mission several times just to get "stuck" on a missile run - sometimes the first, other times after a couple of passes...
When game freezes I can open Task Manager and it says it is running fine. Like reported here before, if I use the manager to "kill" the program DCS displays the message are you sure you want to Exit, before being shut down. I found after the 3rd time that if you Do Alt+Tab show your open tabs and try and force the DCS to shut down by clicking on "X" it displays the message and lets you open the game menu. If you get back to the game it is still stuck, but at least you might end the mission if you had the objectives completed and not lose everything.
Now, after looking at this thread, I did the following changes:
- Changed to FullScreen - I thought it was but option was not selected
- Changed Internal Displays from 1024 every frame to 512
- Changed map icons from All to Fog of War - This because for me it disables the F6 "Missile Camera" so one less thing for the PC to render (I'm guessing....)
I tried again - crappy and laggy images on the mirror, but the Vikhrs no longer created a FPS drop like they used to, at least nothing noticeable. Almost depleted the 16 missiles without a single freeze.
Not sure which of the above changes did the trick, but for me it solved.
Hope this helps