Hi,
I started having the same issues after I did a clean Windows 10 install. After a while of flying I run out of virtual memory (see Windows event log screenshot), my game freezes and crashes and other applications like Discord temporarily freeze up as well. For some reason the DCS log doesn't always show E_OUTOFMEMORY but Windows always says I ran out of virtual memory. This happens both on Syria and Georgia. Sometimes after a few minutes, sometimes it takes more than 20 or 30. Doesn't matter whether I use VR (G2 with OpenXR) or regular flat screen.
Furthermore, I noticed that DCS is using only something like 12-14GB of RAM according to the task manager. However, my RAM is pretty much maxed out at 32GB all the time. I can't see any other program using even remotely as much while I play DCS.
Specs:
Nvidia 3080
32GB DDR4 3600
i7-11700k
Gigabyte Aorus Master Z590
dcs.log
dcs.log.old