Exact same issues here, running Win 10 pro. Profile settings will not work, such as key bindings. Unplugging it causes the mouse to be unresponsive and you get that stupid "boop boop" each time you click. Keys still work. The display of which button I'm pressing on the MFD is also buggy, sometimes it shows trigger all the time and only some buttons show and only sometimes. MFD text also seems to flicker?? Very strange behaviour all around.
I've found a temporary solution though! If you play your games while you have the control panel open, your games will detect the presses as their number. For example, trigger is button 1 in control panel, so games will now detect this as "button 1". You can make a temporary controls profile in your games and attempt to work around the fact you do not have multiple profiles and macros and such so you can at least use the damn thing. Waiting patiently for a driver update I guess.
I'm having a terrible experience with windows 10, not one but TWO of my rather common network adapters are still not supported officially and act very buggy as well. Currently having to use a micro USB wifi adapter, lol.