It cannot. They specifically say it's limited to SteamVR. https://service.viveport.com/hc/en-us/articles/4423262844813-How-to-setup-correct-OpenXR-runtime
Probably because of this, I cannot run the MT version in VR properly. The result is this: https://forum.dcs.world/topic/324309-slideshow-level-stuttering-and-frametime-oscillation-in-vr-vive-pro-2-wireless-adapter/#comment-5201954