So my new x56 throttle is showing consistent ghosting as well. I've tried all the non-warranty-voiding actions like powered hubs, 2.0 vs 3.0 ports, front ports, back ports, removing all other USB devices. Some combinations are worse than others, but there is no combination that eliminated ghosting and I'm working through a ticket with Logi support.
The smoking gun to me is that I have 3 Win 10 machines - My gaming PC, another desktop, and a laptop. When I installed everything in the other desktop and the laptop, to my surprise neither of them showed *any* occurrence of a ghost presses. Beat the heck out of the throttle for 5 full minutes on each and works perfectly. Pop it back into my Gaming PC and ghosting about every 4-5 seconds with throttle movement. That tells me it's some USB/power thing that is unique to my gaming PC and the stick itself is most likely not "defective" in the sense that it is not workable. There is an argument to make that it's still defective in the sense that it is not working properly on my system of choice...I'm not sure how Logi will respond - hopefully they are still responsible for getting it to work.
I'm going to continue to pursue BIOS/firmware/USB driver options as well. Maybe a PCIe USB card, although I'm not sure I understand why that's different than ports off the MB or the back panel...?
My motherboard is a Gigabyte X570-UD w/750w PS new last year.