I am having exactly the same problem.
I have a i7 rig with 3 22in Samsung 2243BWX LCDs that run 57mhz no probelm as I run rfactor, iracing etc at 5040 x 1050
I am running VISTA SP1, and 3 NVIDIA 285in SLI running the latest drivers 182.50.
When I install the game the launcher comes up and I can play in the windowed mode at 1024x768.
When I change the options - video to 5040 x 1050. The launcher restarts and just stays as an icon in the taskbar and NO display of the launcher appears on the main screen - I hear the music etc however no launcher on the screen.
I have uninstalled and reinstalled 4 times with teh same result.
Any pointers? Icannot play and I want to on my 3 screens :doh:
Brad