Yeah that's I agree with what you suggest, or find out the wind in a mission (if possible). I used a CBU-105 I believe and while it impacted, it only hit a few targets, but I'm guessing that was due to spread of the targets rather than any issue with any wind (which I believe there was none).
EDIT: i just came back from a training scenario and it seemed to work fine for me. I mean if there's wind it's not affecting the bomb or munitions significantly.
EricJ's post in CBU-105 was marked as the answer