You're not going to be able to VTOL with any realistic combat load. You can't even VTOL with full internal tanks, nevermind external stores. Standard gameplan for the AV-8B is a STO (short take-off) with tanks and weapons. The VTOL part is used for recovery aboard the ship or back at the field, and even then, you're going to have to be lighter on fuel, outside temperature dependent.
Even if you could hover in a tactical situation, you're not going to be able to employ ordnance. The gun and AIM-9 have minimum airspeed employment restrictions.
We can use the nozzles in BFM situations for some circus tricks, but usually, once you're airborne, just another tactical jet.