Actually, you can just hit left windows - home, and whalla!, it starts itself up completely.
Weapons aren't that hard after everything starts up. Just highlight the weapon profile on the DSMS page of the MFD ( one press of the button ) and then press the weapons master mode button ( I think its M on the keyboard ) to cycle to what mode you want on the HUD. Most of the profiles automatically bring up the correct mode if I remember right. The only hard ones are CCRP and Mavericks, where you need to set the SPI. That and the Sidewinders, which I always have problems remembering how to cycle to lock on the off the nose target. Gun, dumb bombs, rockets are just putting the crosshair over the target.