I have a Ryzen 7 5700 32gb with RX6800XT gpu. I have a Pico 4 - lovely headset, good sweetspot, nice lenses but its a pig to get working with DCS and there seemed to be conflicts with Virtual Desktop and drivers for the gpu. Performance was not great, a fair bit of latency (even with a dedicated access point) and not a particularly good framerate. Your rig may handle it a bit better.
Because of all the issues with the Pico, I got a 2nd hand Reverb G2 (v1). The sweetspot is poor but it connects and runs without some of the issues I had with the Pico. Runs quite smoothly, just wish sweetspot was better. This was improved a smidgen with a VRCover facial interface. Not had issues with v1 cable (yet) but have bought a spare V2 cable in case the V1 fails.
Another point to consider is accessories - Pico accessories are cheap (prescription lenses £10 for the Pico, £60 for the G2).
If you think your rig can handle it - Pico 4. Although in the "giving up on Pico 4" thread someone with AMD 5800X3D, 3080Ti, 64GB Ram system wasn't happy with the performance. The Pico 4 price occasionally drops to £320 on Amazon and very occasionally to £300.
I should also add that I started with Quest 2 for a couple of weeks but wasn't impressed so bought the Pico thinking my system could handle it.