We have a lot of nVidia Users here. So would anybody so kind to try the following:
Go into the nVidia Control Panel. Go to "Sourround, PhysX" Menue. Switch the PhysX-Setting from "Auto" (which adresses the nVidia Card) to "CPU".
As long as I have PhysX bound to CPU, I haven't had a 2nd Load crash like before. As soon as I switch back to "Auto" oder "GPU", the crashes start all over again. I could switch the crashes on and off via this setting on my machine. That must not be true for anybody else. But I think it would be worth a few Tests.
Oh, and of course don't use the Compat. Mode while testing this as that wouldn't be the same.
If the new Clouds use some kind of PhysX, that would make sense. At least for nVidia Users. Sorry that I can't test on AMD Hardware as I sold my Vega 64 a few months ago...