I have done a little more testing tonight. I have been reviewing other threads with similar issues but none of the solutions that worked for others seem to match what i am experiencing. this does seem related to the graphics settings though. here are additional tests i have done.
1. turned off antivirus. no difference.
2. removed the DCS.openbeta folder from Saved Games. this made some difference as the graphics setting were reset to default. everything seems fine then, but i really do not want to play the game in a 1280x768 window on a 2560x1440 monitor.
3. i started working on the graphics settings, changing one thing at a time. i worked up to my preferred resolution, 3200x1800 virtual super resolution. that worked fine.
4. i then set the preset to medium, that works fine.
5. i then set the preset to high, and the game started crashing either just before entering the 3d world (before you can hit fly - still on loading screen) or within a few seconds of entering the 3d world after hitting fly.
6. i then used the medium preset and changed one setting at a time. it turns out it is either of two settings that cause the issue i am seeing: textures and water. when either is set to high, the game locks with the symptoms in the first post. so i can use 3200x1800 with the high preset as long as i set textures and water to medium.
if i can do more testing to gather more data, let me know. i do run other games with this virtual super resolution and high settings with no issues.
i CAN change to an NVIDIA card to test as well if that data would be useful. i prefer not to (key activations) but i can. i cannot test in 2.0 as i do not have nttr.