Hello
I once had this problem with the warthog setup, I was told to make sure you are running DCS as administrator. I cleaned out all my joystick throttle pedals assignments including axis but NOT the KB assignments. Then I started over with fresh assignments and it was corrected.
Also make sure you are running you hotas male USB connectors on your system USBs rather than on stand alone USB extension.
Also I would get this Smart Utility that helps you see what devices are connected to your USB port within Windows Clean up old connections streamline your connections
https://downloads.tomsguide.com/USBDeview,0301-13254.html
I hope this helps