Happened to me again just now.
This has happened multiple times on the same SP mission.
Freshly started DCS and mission.
Flying SP mission, Caucasus. (Mission file attached to this post.)
Just started up. Took off from carrier, flew to AO. WPT1.
Have Gun selected
Press PAL lock with an enemy helicopter in sights.
Instant CTD, no errors.
Log file does not indicate any crash error, but can be supplied on request.
Latest DCS.
No mods.
No programs running except TrackIR.
nVidia GTX 980, driver 430.53 Defend the Storage Depot CAUC 2.5b5.miz