I´m not sure, since I haven´t really experimented with it that much.
But I guess that a target designated with the AG Radar will override the position loaded into the JDAM, thus You need to undesignate the AG Radar target.
Regarding the TPOD, this might work a bit different depending on whether the TPOD CDES is boxed or not.
Theoretically designating a target with the TPOD and CDES unboxed, will only designate at the moment You press designate and keep that spot as the designated target point also if You start moving the TPOD around.
With CDES boxed in will continually designate the position where the TPOD is looking
Question is just if there is a need to undesignate the TPOD before dropping JDAM's with positions ,oaded into weapon memory.
Until now I have undesignated both AG radar and / or TPOD before dropping JDAM's with good result.