I've been working on narrow body 320 and 737(CL&NG) families for the last 5.5 years. If you ask for RL I can tell you that your favourite has a huge disadvantage exactly because of it's crappy engine. The V2500 is junk. From all the types I'm licensed (319/320/321 (both CFM and IAE), 737CL and 737NG) I prefer the NG the most from all points of view - more reliable, flies better, flies further and most important - it's metal, not plastic :D
On the wide body scene AIB though has some strong players. I don't have 1st hand experience on them but I recognize the 330 as a very good piece of engineering.